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Dear Yiquan, the option appears only if you have previously defined an F-contrat (the ensuing adjustment is with respect to the null space of that contrast). The relevant SPM function is spm_regions.m. Best regards, Guillaume. s yq wrote: > Dear SPMers, > > I want to extract the adjusted time course of some ROIs, however, after > I click the ' VOI' button (in SPM 5) and name the VOI, it was > automatically selected ' don't just ' and jumped to the next step. Would > anyone tell me what could be the reason of this problem or which m file > in SPM is doing these operations? Thank you very much. > > Best regards > Yiquan > > > LMU München > D-80802, München -- Guillaume Flandin, PhD Wellcome Trust Centre for Neuroimaging University College London 12 Queen Square London WC1N 3BG