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Hi Justin, Are you running Analysis as a 32bit compile? (Or on a 32bit OS / system?) 32bit machines have a 2G file limit... (If you're not, would you mind letting us know you are running and we can have a go at fixing it!) Dan PS The maximum spec size isn't limited by your RAM, but if you exceed your RAM you will *certainly* experience poor performance (we're thinking about how to fix this). PPS A little explanation http://linuxmafia.com/faq/VALinux-kb/2gb-filesize-limit.html On 17 Feb 2010, at 12:52, Justin Lecher wrote: > On 17/02/10 13:50, Lecher, Justin wrote: >> Hi all, >> >> Could it be that the maximum spectra size is limited by the amount of >> memory I have? >> >> I can open a spectra 1.9GB size w/o any problem, but a 2GB spectrum >> crashes analysis. My box has 2GB of memory. >> >> justin >> >> > > Oh I forgot, > > it crashes python with a buffer overflow detection. > > justin > > -- > Justin Lecher > Institute for Neuroscience and Biophysics > ISB 3 - Institute for structural biochemistry > Research Centre Juelich GmbH, > 52425 Juelich,Germany > phone: +49 2461 61 5385 > > > > Daniel O'Donovan [log in to unmask]