The Malvern is indeed very nice. The only issue I have with ours is that it doesn't do plates. This makes buffer screening a very laborious busy that is best left to graduate students. Andreas On 04/02/2010 2:22, Savvas Savvides wrote: > Hi Wojtek > I can easily second Dave's comment! > Best > Savvas > > ---- > Savvas Savvides > Unit for Structural Biology @ L-ProBE > Ghent University > K.L. Ledeganckstraat 35, 9000 Ghent, Belgium > Ph. +32 (0)472 928 519 > http://www.LProBE.ugent.be/xray.html > > > On 04/02/10 14:54, "David Briggs"<[log in to unmask]> wrote: > >> Hiya. >> >> My two penneth on the Malvern Zetasizer. >> >> Simple, idiot-proof operation. Software is easy and intuative. Reports >> are customisable to give you what information you want. >> Problems easy to trouble shoot IMHO. >> >> Does DLS, SLS, melting point determination. >> >> After-care support is good from Malvern. >> >> Not used the Wyatt instrument. >> >> HTH, >> >> Dave >> >> ============================ >> David C. Briggs PhD >> Father, Structural Biologist and Sceptic >> ============================ >> University of Manchester E-mail: >> [log in to unmask] >> ============================ >> Internetz: http://xtaldave.posterous.com/ >> Twitter: @xtaldave >> Skype: DocDCB >> ============================ >> >> >> >> On 4 February 2010 13:36, Wojciech Rypniewski<[log in to unmask]> wrote: >>> Dear Fellow Crystallographers >>> >>> We are going to buy a DLS instrument to help us assess crystallizability >>> of our proteins. I would be grateful for any opinions - either >>> on this BB or in my mail box (in which case I'll keep them to myself, >>> naturally). >>> >>> We have looked more closely at two instruments: >>> >>> DynaPro NanoStar from Wyatt and >>> Zetasizer Micro V from Malvern >>> >>> and both seem to be rather similar in terms of parameters and price. >>> >>> I would appreciate user opinions as to the reliability, >>> ease of use or any features that make a given instrument >>> particularly suited for assessing biological samples. >>> >>> Many thanks, >>> >>> Wojtek >>> >>> -- >>> ---------------------------------------------------------------------- >>> Prof. dr hab. Wojciech Rypniewski tel: +48-61-8528503 >>> Institute of Bioorganic Chemistry fax: +48-61-8520532 >>> Polish Academy of Sciences e-mail: [log in to unmask] >>> Noskowskiego 12/14 www: www.man.poznan.pl/~wojtekr/ >>> 61-704 Poznan, Poland >>> ---------------------------------------------------------------------- >>> > -- Andreas Förster, Research Associate Paul Freemont & Xiaodong Zhang Labs Department of Biochemistry, Imperial College London http://www.msf.bio.ic.ac.uk