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Dear Jane, 

If you rename one of domains with a different chain ID (in the PDB) you can submit the structure to PISA (http://www.ebi.ac.uk/msd-srv/prot_int/pistart.html) and it will do the job.
Regards
Rafa
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Rafael Fernández Leiro
Departamento de Biología Celular y Molecular
Facultad de Ciencias
Universidade da Coruña
Campus de A Zapateira s/n
E-15071 La Coruña (Spain)
Phone: +34 981 167 000 / 2136 (Lab.)
           +34 666 003 613            (Home)
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El 19/02/2010, a las 16:42, Jane Bailey escribió:

> Dear all,
> 
> I am trying to calculate the domain-domain contact surface from one chain. I see AREAIMOL to only tell you the accessible surface area/residue. Could any other software/webserve could specify residues in the contact surface and calculate the total contact area?
> 
> Thanks
> 
> J.