Any chance that it is myristate or some other fatty
acid?
Good luck-
Steve
On Fri, Feb 19, 2010 at 3:42 AM, Marek Frischerkase
<[log in to unmask]>
wrote:
Hello,
sorry for my off topic question.
I found a PEG
molecule bound to the active site of my enzyme structure. And I did not
expected it there, though I used PEG as precipitant in the
crystallization condition. Now I'm wondering how could bind PEG with its
hydrophobic nature at all in the hydrophobic active site? It seems that
the PEG molecule interacts predominantly with Tryptophans (distance 3.8
A). Did anybody observe similar cases? And which kind of interaction
should there be active? I would be grateful for your
help,
cheers,
Marek
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