Dear SPMers, Apologies if this is a rather basic question. I have been analysing some straighforward finger tapping data in SPM2 (we started in this version so sticking to it for now). I have analysed it as event-related with temporal derivatives and added in the movement parameters as covariates at the first level. With the resultant con images I have used the basic t-test to create a group map (n=53). I have also used the con images in a simple regression using a clinical measure of parkinsonism. All good so far. However, I would now like to perform a basic t-test and input the clinical measure (of which there is only one data point per person) as a covariate of no interest. As I see it , the only way I can do this is using the AnCova, however, because I only have one group this doesn't seem appropriate (although I have tried and it crashes anyway!). Does anyone know if there a method by which I can acheive this? Any help would be greatly appreciated. With best wishes Cath