Hi Heather,
 
what was the total number of cases you used for this comparision please?
 
many thanks
 

Tracy

Tracy Huguenel, RGN, SCPHN (OH)
Deputy Head of Occupational Health
0845 155 3111 Ext 3982 / 3591
Fax 01268 534127

 


From: [log in to unmask] [mailto:[log in to unmask]] On Behalf Of Heather Bearpark
Sent: 15 January 2010 09:13
To: [log in to unmask]
Subject: [OCC-HEALTH] Hep B seroconversion rates

I am posting this to both HEOPS and OH JISC mail groups as I think it may be of interest to you in both NHS and HE settings.  Apologies if you get this twice!
We did a fast and dirty comparison of seroconversion rates for the old schedule of 0,1,6 months and test at 4 - 6 weeks vs the new accelerated schedule 0, 1, 2 months + test at 4 - 6 weeks after. I only included people who had stuck to the exact regime.
This is what we found:
After 3 doses accelerated there was 70% seroconversion to >100Iu and 24% achieved immunity at 10 - 99 Iu thus requiring a 4th dose of vaccine.
After 3 doses old standard course we achieved 80% > 100 Iu with a further 14% achieving 10 - 99 Iu on the same schedule.
Where the immune level was 10 - 99 Iu we gave a 4th dose and did not retest since 10 Iu is deemed as sufficient.
Our team evaluated this and felt that it was preferable to continue with the accelerated course as we can fit the students in more easily before they are lost out onto clinical placement. This weighed up against having to give a 4th dose of vaccine to an additional 1 in 10 of them.
We also feel that we are getting better attendance rates when there is only one month between the appointments rather than the long 5 month break as previously so this has decreased the admin workload.
 
 
Regards
Heather Bearpark
Occupational Health Manager
RN, Specialist Community Public Health Nurse (OH), Cert IOSH
 
University of Huddersfield 
Tel +44 (0)1484 47 1800
Fax +44 (0)1484 47 3360
heather.[log in to unmask]
www.hud.ac.uk/oh
 
 
 

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