After the success in number of applications, a gentle reminder before the close deadline (next Sunday)!


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Practical workshop on the use of longer wavelengths in Structural Biology

*The routine accessibility, on some macromolecular crystallography (MX)
beamlines at SR sources, of photons in the energy range 8 – 6 keV has
lead to an increase in the exploitation, for structure solution in MX,
of the small anomalous signals from sulphur and phosphorous available at
such energies. However, due to experimental difficulties, this approach
to structure solution has not yet reached its full potential.

A Practical Workshop on the use of longer wavelengths in Structural
Biology* *will be organised at the ESRF, Grenoble on the 18th-19th of
February 2010. Long wavelength data will be collected on the ID29 MAD
Beamline which is equipped to provide state-of-the-art facilities for
long wavelength data collection (i.e. third harmonic rejection mirror,
use of minikappa device to reorient the crystals for more accurate
Friedel pairs measurement and use of He-filled cone to minimise air
scattering and absorption).

The number of participants is limited to six. Students will be tutored
directly on the beam line where data processing and on-line attempts at
structure solution will also take place. Participants are encouraged and
should be prepared to bring crystals of their own 'real' cases where
phasing using longer wavelengths (particularly S-SAD or P-SAD) might
prove tractable.

Travel and subsistence costs will be covered by the ESRF. Applications
comprising a full CV, a letter of motivation, a supporting letter from
the supervisor and a detailed characterisation of the sample (cell
parameters, number of anomalous scatterers, resolution limit, space
group, DF/F etc) should be sent electronically to
[log in to unmask] before the *24th of January 2010*.

Information are available on the course web page http://www.esrf.eu/events/conferences/Long%20Wavelength%20workshop


On behalf of the organisers

Claudine Brun, Daniele de Sanctis, Gordon Leonard, Christoph
Mueller-Dieckmann

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Daniele de Sanctis, PhD

Structural Biology Group
ESRF, Grenoble, France
Tel 33 (0)4 76 88 2869