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http://hamptonresearch.com/documents/product/hr000175_what_is_tacsimate_new.pdf turns up once you use google's "I'm feeling lucky" button. On Tue, 2010-01-26 at 15:42 +0000, Zhiyi Wei wrote: > Dear all, > > I got a problem with my crystals. I have two total different proteins > that both can be crystallized in the condition with PEG3350 and Tacsimate > (although the concentrations are different) with different shapes. The > crystals look big and beautiful. However, when I test them in synchrotron, > both of these two types of crystals showed poor diffractions. As showed in > the attached diffraction image, the diffraction is up to ~4 A but smear in > one direction while <8 A in the other direction. The interesting thing is > that the diffraction pattern is similar for all crystals (from two different > proteins) that I tested without exception although they belong to different > space groups. So, I wonder whether these kind of pattern is caused by > Tacsimate (I don't know what it is) and how to rescue these crystals. Any > suggestions or comments? > > Thanks a lot! > > Best, > Zhiyi -- Edwin Pozharski, PhD, Assistant Professor University of Maryland, Baltimore ---------------------------------------------- When the Way is forgotten duty and justice appear; Then knowledge and wisdom are born along with hypocrisy. When harmonious relationships dissolve then respect and devotion arise; When a nation falls to chaos then loyalty and patriotism are born. ------------------------------ / Lao Tse /