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Dear Martin, Donald and SPM-list, I have exactly the same problem, so any additional comments would be greatly appreciated! Thanks in advance, Andreas. Martin Dietz schrieb: > Dear Donald, > > I have of course thought of the same, which works perfectly for a > one-session paradigm. However, the paradigm is somatic stimulation > rest > (condition A - rest) and (condition B - rest) obtained in two different > scanning sessions in the same group of patients. It is therefore not valid > to assume the same 'baseline' and simply contrast A>B at the first level. > > I have created the contrast images with ImCalc but I am not completely sure > how this is valid compared to the paired t-test where subject offsets are > accounted for? > > Best regards, > Martin > > >