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An opening for a Post-doctoral position is available starting January 15th in the Structural Basis of Genome Integrity Group at the Spanish National Cancer Research Centre in Madrid (CNIO). The ideal candidate should have a PhD in structural biology, biochemistry or a related field and should have experience in molecular biology, protein expression and purification. Additional experience in macromolecular X-ray crystallography and/or single-particle electron microscopy is highly desirable. Experience with protein expression in eukaryotic systems is an advantage. Fluency in English required. The research focuses on structural and functional aspects of genome integrity, with particular emphasis on employing X-ray crystallography and single-particle electron microscopy to elucidate the structures and understand the function of large macromolecular complexes involved in DNA recombination and repair. The candidate will work with a team of highly motivated structural biologists and biochemists and collaborate with cell biology and computational groups at the CNIO. The Structural Basis of Genome Integrity Group is a newly established research group led by Dr. Santiago Ramon-Maiques who recently moved to the CNIO from the Institute of Biomedicine of Valencia, and previously worked in the group of Dr. Wei Yang at the National Institutes of Health, in Bethesda. We offer: o An appointment for a period of one year with the possibility of extension up to five years. o A competitive salary and an attractive benefits package. o Access to state-of-the-art facilities for X-ray crystallography and electron microscopy. o The opportunity to be part of a European Cancer Research Centre of excellence that successfully combines basic and applied research. Applications can be sent at any time, preferably before 1st of January 2010. Applicants should submit a CV, a statement of research interests, and the names and contact information of two references to Santiago Ramon-Maiques ([log in to unmask]). All enquiries and applications will be treated confidentially.