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MEDICAL RESEARCH FUNDING :
STEM CELL RESEARCH:
Recovery Act Funds Expand Studies of Stem Cell Biology



Date: Wed, 28 Oct 2009 12:50:46 -0400
From: "NIH OLIB (NIH/OD)" <[log in to unmask]>
To: [log in to unmask]
Subject:  Recovery Act Funds Expand Studies of Stem Cell Biology



U.S. Department of Health and Human Services
NATIONAL INSTITUTES OF HEALTH NIH News


National Institute of General Medical Sciences (NIGMS)
<http://www.nigms.nih.gov/>



For Immediate Release: Wednesday, October 28, 2009



CONTACT:

Ann Dieffenbach, NIGMS

301-496-7301

e-mail:

[log in to unmask]




RECOVERY ACT FUNDS EXPAND STUDIES OF STEM CELL BIOLOGY



The National Institute of General Medical Sciences (NIGMS), part of the 
National Institutes of Health, is using $5.4 million of Recovery Act funds 
to accelerate basic studies of induced pluripotent stem cells. These 
cells, abbreviated iPS, are reprogrammed from skin or other easily 
obtained adult cells and appear to be similar to stem cells derived from 
embryos.

In theory, iPS cells could generate any type of cell and be used to treat 
diseases. But to realize this potential, scientists need a much better 
understanding of iPS cells' fundamental properties and how to efficiently 
derive cells that are safe for therapeutic uses.

To speed iPS research, NIGMS has awarded one-year grant supplements to 22 
scientists at 16 institutions in 12 states and the District of Columbia. 
The investigators already have strong records of accomplishment in a range 
of research areas and will study iPS cells in varied biological systems.

"Stem cell biology is poised for rapid advances, and we expect our 
Recovery Act investment to have a catalytic effect. The new awards will 
contribute to the field's progress by enhancing the utility of iPS cells 
as tools for research, for testing the effects of drugs on human tissues 
and ultimately for patient-specific treatments," said NIGMS Director 
Jeremy M. Berg, Ph.D.


The Recovery Act funding will allow the scientists to address such 
important questions as:


-- How does reprogramming work?

-- What factors are necessary to create iPS cells efficiently and safely?

-- What drives iPS cells toward a desired cell type that can be used to 
regenerate or repair damaged tissues in a patient?

-- Do iPS cells differ from embryonic and adult stem cells, and if so, 
how?



The investigators receiving supplements are:



-- Bruce Beutler, Scripps Research Institute, La Jolla, Calif.

-- C. Anthony Blau, University of Washington, Seattle

-- Richard Cerione, Cornell University, Ithaca, N.Y.

-- Stephen Dalton, University of Georgia, Athens

-- Sharon Dent, University of Texas M.D. Anderson Cancer Center, Houston

-- Andres Garcia, Georgia Institute of Technology, Atlanta

-- David Gilbert, Florida State University, Tallahassee

-- Margaret Goodell, Baylor College of Medicine, Houston

-- Brenton Graveley, University of Connecticut Health Center, Farmington

-- Jeanne Lawrence, University of Massachusetts Medical School, Worcester

-- Jeannie Lee, Massachusetts General Hospital, Boston

-- Shaohua Li, University of Medicine and Dentistry of New Jersey/Robert 
Wood Johnson Medical School, Piscataway

-- John Lis, Cornell University, Ithaca, N.Y.

-- Nancy Maizels, University of Washington, Seattle

-- Sergie Nekhai, Howard University, Washington, D.C.

-- Sean Palecek, University of Wisconsin-Madison

-- Arnold Rizzino, University of Nebraska Medical Center, Omaha

-- Hannele Ruohola-Baker, University of Washington, Seattle

-- James Thomson, University of Wisconsin-Madison

-- Yi Wang, Baylor College of Medicine, Houston

-- Jeffrey Wilusz, Colorado State University, Fort Collins

-- Jerome Zack, University of California, Los Angeles



For project details, go to



<http://projectreporter.nih.gov/reporter.cfm>



check the box that says "Show only projects supported by NIH Recovery Act 
funds," and enter the name of the scientist in the Principal Investigator 
field.


To download a high-resolution image of an iPS cell, go to



<http://images.nigms.nih.gov/index.cfm?event=
downloadFile&imageID=2604&filename=Thomson_IPS_cells09.jpg>



NIGMS is a part of NIH that supports basic research to increase our 
understanding of life processes and lay the foundation for advances in 
disease diagnosis, treatment and prevention. For more information on the 
Institute's research and training programs, see


<http://www.nigms.nih.gov>


The National Institutes of Health (NIH) - The Nation's Medical Research 
Agency - includes 27 Institutes and Centers and is a component of the U.S. 
Department of Health and Human Services. It is the primary Federal agency 
for conducting and supporting basic, clinical, and translational medical 
research, and it investigates the causes, treatments, and cures for both 
common and rare diseases. For more information about NIH and its programs, 
visit



<http://www.nih.gov>



The National Institutes of Health (NIH) -- The Nation's Medical Research 
Agency -- includes 27 Institutes and Centers and is a component of the 
U.S. Department of Health and Human Services. It is the primary federal 
agency for conducting and supporting basic, clinical and translational 
medical research, and it investigates the causes, treatments, and cures 
for both common and rare diseases. For more information about NIH and its 
programs, visit



<http://www.nih.gov>


-----------------------------



The activities described in this release are being funded through the 
American Recovery and Reinvestment Act (ARRA). More information about 
NIH's ARRA grant funding opportunities can be found at


<http://grants.nih.gov/recovery/>


To track the progress of HHS activities funded through the ARRA, visit


<http://www.hhs.gov/recovery>


To track all federal 
funds provided through the ARRA, visit



<http://www.recovery.gov>



##



This NIH News Release is available online at:
<http://www.nih.gov/news/health/oct2009/nigms-28a.htm>






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