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Dear Gonzalo,


There is a utility called Image Calculator. In the easiest case, you do "i1-i2" and that's it.

However, that's unlikely to be what you want, because you're unlikely to have fully quantified FDG parametric maps, hence you'll need to account for global differences etc. - and then you'll quickly be back to the SISCOM literature and Woo-Suk's suggestions.

It can all be done in SPM, though - computing globals, scaling, subtracting, thresholding... mainly with the Image Calculator.

Good luck,

Alexander






---------------------------------
Alexander Hammers, MD PhD



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On 5 Oct 2009, at 18:05, Gonzalo Rojas wrote:

Hi:

 And with SPM... How can I compute such difference ?...

 Sincerely,


Gonzalo Rojas Costa
Department of Radiology
Las Condes Clinic
Lo Fontecilla 441, Las Condes, Santiago, Chile.
Tel: 56-2-2105170
Cel: 56-9-97771785
www.clc.cl


Woo-Suk, Tae escribió:
Hi,


You coud it with ISAS ( http://spect.yale.edu
<http://spect.yale.edu/> ), RVIEW
(http://www.colin-studholme.net/software/software.html ),

or SISCOM procedure of ANALYZE package (see Dr. O'Brien's SISCOM paper).


Best regard!


Woo-Suk, Tae
Chuncheon, Korea




   --- Original Message ---
   *From : *"Gonzalo Rojas"<[log in to unmask]>
   *To : *[log in to unmask]
   *Date : *2009/10/05 월요일 오후 1:17:05
   *Subject : *[SPM] difference between two PET studies of same patient...

   Hi:

   I have two FDG-PET images of the same patient acquired in different
   days... How can I get the difference between those images ?...

   Sincerely,


   --
   Gonzalo Rojas Costa
   Department of Radiology
   Las Condes Clinic
   Lo Fontecilla 441, Las Condes, Santiago, Chile.
   Tel: 56-2-2105170
   Cel: 56-9-97771785
   www.clc.cl