Dear CCP4 users,<br><br>I am trying to improve MR phases using multi-crystal averaging in DMMULTI. First crystal has  3 fold NCS , 5A resolution and the second crystal no NCS , 4A resolution.<br>I ask for your advice concerning two issues ;<br>
<br>In the first cycle DMMULTI calculates solvent masks for the two crystals. Does it continously improve these masks or stick to the initial one ?<br>Since DMMULTI does not apply gamma-perturbation (solvent flipping) should I use it to the highest common resolution (5A) only and continue with DM/PARROT to 4A  ?<br>
<br>Thank you for your time and advice,<br><br>Peter<br><br><br><br><br>