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I can suggest the following reading
Discovering novel ligands for macromolecules uisng X-ray crystallographic screening
Nienaber VL et al, Nature Biotechnology vol 18 october 2000 pp1105



--
Pascal F. Egea, PhD
Assistant Professor
UCLA, David Geffen School of Medicine
Department of Biological Chemistry
314 Biomedical Sciences Research Building
office (310)-983-3515
lab (310)-983-3516
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