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What a disgraceful (slanderous/libel Not in my lab it isn't!!!!! What a disgraceful (slanderous/libellous) statement to make. Pre-analytical factors may well be commonest overall cause but thrombocytosis tops my list by miles. I see at least one patient a week being treated with Ca gluconate, Ins/Dex and salbutamol nebulisers in an attempt to lower a pseudohyperkalaemia. When I phone to request a plasma (Li Hep) sample, I've seen the K differ by 2.4mmol/L. I have arranged with Haem to put an auto-comment on platelets above 700, but I see this effect below that level. It depends on the increase from the patient's basal platelet count. The ones who really concern me are those with serum K of 3-3.5 with high platelets who are actually hypokalaemic but we don't trap those K levels on NPCL. Regards Gail Dr Gail Curtis Principal Biochemist Dept of Chemical Pathology Ysbyty Glan Clwyd 01745 445293 **Please consider the environment before printing - Diolch yn fawr** -----Original Message----- From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Ian Barlow Sent: 30 October 2009 15:49 To: [log in to unmask] Subject: Re: The most abundant cation in the human body? It is interesting that laboratory error is at the top of the list of causes of spurious hyperkalaemia. Box 1 Causes of spurious hyperkalaemia Laboratory error Delayed analysis Blood collected from vein into which potassium is infused Excessive tourniquet or repeated fist clenching Haemolysis via small needle or traumatic venepuncture Prolonged storage of blood Severe leucocytosis or thrombocytosis Uncommon genetic disorders (familial pseudohyperkalaemia) Discuss? Have a good weekend. Ian -----Original Message----- From: Clinical biochemistry discussion list [mailto:[log in to unmask]] On Behalf Of Nick Miller Sent: 30 October 2009 12:39 To: [log in to unmask] Subject: Re: The most abundant cation in the human body? I think someone forgot about hydrogen Nick Miller, London 2009/10/29 Jonathan Kay <[log in to unmask]>: > Today's BMJ > > Hyperkalaemia -- Nyirenda et al. 339: b4114 -- BMJ > > http://www.bmj.com/cgi/content/full/339/oct23_1/b4114 > > "Potassium is the most abundant cation in the human body" > > Discuss? > > Jonathan > > > ------ACB discussion List Information-------- This is an open discussion > list for the academic and clinical community working in clinical > biochemistry. Please note, archived messages are public and can be viewed > via the internet. Views expressed are those of the individual and they are > responsible for all message content. ACB Web Site http://www.acb.org.uk List > Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List > Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ Central Area of North Wales NHS Trust - Email Notice (2009) You are advised to read (and print for future reference) the Central Area of North Wales NHS Trust e-mail notice which can be found at this location http://www.wales.nhs.uk/sites3/page.cfm?orgid=115&pid=12672 Rhybudd Ebost (2009) - Rhanbarth Canolog o Ymddiriedolaeth GIG Gogledd Cymru Fe'ch cynghorir i ddarllen rhybydd ebost yr Ymddiriedolaeth (a'i argraffu er mwyn cyfeirio ato yn y dyfodol). Gellir dod o hyd iddo yn y lleoliad canlynol http://www.wales.nhs.uk/sites3/w-page.cfm?orgid=115&pid=12671 ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/