Dear SPM'ers, I am wondering whether or not it is advisable to use DARTEL to perform normalization of fMRI data in a study in which we have 4 different groups (orbitofrontal lesions, lateral PFC lesions, medial PFC lesions and a control group). I am currently using the SPM8 unified segmentation/normalization with mixed results, and am in search of something more robust. Any tips/pointers would be greatly appreciated. Best wishes, h.