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The FCC's report to the President (June 2009) emphasizes that comparative effectiveness research, by their definition, must be conducted in "real world" settings. However, I have been unsuccessful in finding a more specific definition for "real world," either from AHRQ or from anyone else. Has anyone seen anything that lists the essential elements of a "real world" setting, or specific elements that would make it definitively NOT "real world"? (Not necessarily an official government definition, I'll take anything at all.) I'm guessing it might include things like sample characteristics (not all college sophomores), provider characteristics, logistical issues, or even the physical setting...Any help would be appreciated, thanks. Teresa Benson, M.A., Licensed Psychologist Senior Clinical Content Specialist, InterQual Products McKesson Health Solutions 18211 Yorkshire Avenue Prior Lake, MN 55372 USA [log in to unmask] <mailto:[log in to unmask]>