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You need of 95% confidence intervals to estimate uncertainty around the point estimate (in your example NNT 25)

Any NNT without 95% CIs is useless

 

 

Regards

 

Nino Cartabellotta

Director

 

Centro Studi GIMBE®

Via Amendola 2 - 40121 Bologna

Tel. (+39) 051 5883920 

Fax (+39) 051 3372195
www.gimbe.org

 

 


Da: Evidence based health (EBH) [mailto:[log in to unmask]] Per conto di Jon Brassey
Inviato: luned́ 3 agosto 2009 13.59
A: [log in to unmask]
Oggetto: Uncertainty

 

Hello All,

 

I may be missing the point, but do others get frustrated with the term uncertainty in medicine? I've just received another pile of promotional material from a publisher who's highlighting uncertainty in medicine and insinuating their evidence is the answer.  Surely, 'all' evidence does is quantify the uncertainty?  For instance a drug may have a NNT of 25 - where's the certainty in that?

 

Here's hoping for some serious and lighthearted responses.

 

Best wishes

 

jon

 

Jon Brassey

TRIP Database

www.tripdatabase.com