May be you can use "modeller" to model the apo structure using the structure of complex as template.
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Date: 2009年8月9日(星期天) 晚上8:37
Subject: [ccp4bb] How to model apo protein structure from solved ligand bound high resolution structure?
Dear CCP4ers,
Recently we have solved two structures from E.coli in high resolution, which have bound two different ligands tightly already. Here I want to know if there is any program which can let us model the structure of our apo proteins confidently. Thanks ahead for any comment and input.
Regards,
Donghui
