Hi, Our current recommendation for this problem is to truncate the top 5-8% of the images intensity values with fslmaths before classification, see the thread "Fast - strange misclassification" for more details. Many Regards Matthew > Hello, > > I was wondering if there has been any update on this extreme dark/ > bright > classification issue. I am trying segment WMH on FLAIR images. WMH are > located around the CSF. I do a skull strip on T1 and mask the FLAIR > image > using this mask and feed the stripped image to FAST. The number of > classes in > FAST is set to 3. FAST tends to merge extreme dark (CSF) and extreme > bright > (WMH) and provide one class. > > I am using FSL version 4.1.2 and FAST version 4.1. I noticed there > is already > an update on FSL. If this issue has been addressed, I will update to > the new > version. If there is any work around, please let me know as well. > > Thank you very much.. > > Deniz > > > On Thu, 2 Apr 2009 10:15:58 +0100, Matthew Webster > <[log in to unmask]> wrote: > >> Hi, >> The thresh.txt needs 1 value for each class ( 4 in your case ) >> which are the _log_ values of the means ( we will be changing the >> inputs back to normal intensities in the next release ). We're >> currently looking into the extreme dark/bright classification >> issue... >> >> Many Regards >> >> Matthew >> >>> Hi, I wanted to identify white matter hyperintensities in a >>> carefully cleaned up flair image >>> (Betted and Grey matter and ventricles pretty well removed). >>> I was hoping that the -s (or --manualseg) option in fast would allow >>> me to choose a starting value that characterized my wmh, >>> but when I try that: >>> >>>> fast -s thresh.txt combo >>> >>> (thresh.txt contains a single number, 722 which is 3 SD above the >>> mean) >>> >>> It seems to be doing something else (it lumps together very dark and >>> very bright patches....even when I have 4 classes). >>> Can anyone explain more about manualseg and how to use it? I've >>> looked at the online materials and the forum, but I'm afraid I don't >>> see much that is helpful. >>> >>> Thanks for any insights. >>> >>> -Dianne >>> >>> -- >>> Dianne Patterson, Ph.D. >>> [log in to unmask] >>> University of Arizona >>> SLHS 328 >>> 621-5105 >> >> >