Sorry, substitute 2 for 4, I didn't at first realize your images are already in 2mm voxels. Peace, Matt. -----Original Message----- From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Matt Glasser Sent: Friday, July 17, 2009 1:53 PM To: [log in to unmask] Subject: Re: [FSL] downsampling resolution I would use something like flirt -interp nearestneighbour -in <mask> -ref <mask> -applyisoxfm 4 -out <mask_4mm> Peace, Matt. -----Original Message----- From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On Behalf Of Enzo Tagliazucchi Sent: Friday, July 17, 2009 12:49 PM To: [log in to unmask] Subject: [FSL] downsampling resolution Hi all, I've got a set of masks mapped to the MNI152 template at 91X109X91 resolution. I want to downsample this masks and get a 45X54X45 resolution ( 4mm X 4mm X 4mm) voxels. Is there a more or less standard procedure to do this? I've been tinkering with ApplyXFM and Flirt but I'm not getting consistent results... thanks all! Enzo.