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I have a P62 crystal that is probably p31 (or P32). When I run the detwin program to actually output detwinned data, do I input the mtz as processed (e.g. as output from dtrek or HKL2000) in the wrong (higher symmetry) or the correct space group - Thanks Laurie Betts University of Pittsburgh X-ray Crystallography Facility Manager Department of Structural Biology 3501 Fifth Avenue, Pittsburgh, PA 15260 412-383-5839 [log in to unmask]