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The cost of a red cell transketolase assay should keep the patient in thiamine tablets (GPB0.79 for 20) for many years. with best wishes Richard Richard Mainwaring-Burton Consultant Biochemist Queen Mary's Hospital (NHS mail a/c) Sidcup, Kent 020-8308-3084 [log in to unmask] _____ From: Clinical biochemistry discussion list [[log in to unmask]] On Behalf Of Ceridwen Coulson [[log in to unmask]] Sent: 15 July 2009 09:24 To: [log in to unmask] Subject: Thiamine deficiency Dear All, Have a persistent request for trying to confirm a diagnosis of thiamine deficiency on a patient who has been in our ITU, now with Neurology. She has been on vitamin supplementation for 2 weeks, and is improving. Being pressed to see if any way of now confirming a diagnosis, either with a current test, or on any retrospective samples that might be around our assorted labs in North Bristol. I've tried to damp down their hopes, but just said I'd ask our expert mailbase! Blood or urine or any other body fluid? Thiamine itself or red cell transketolase? Would welcome any ideas, or reinforcement that too late now to confirm with a biochemical test. many thanks, Ceridwen North Bristol NHS Trust - www.nbt.nhs.uk DISCLAIMER: The information in this message is confidential and may be legally privileged. It is intended solely for the addressee. Access to this message by anyone else is unauthorised. If you are not the intended recipient, any disclosure, copying, or distribution of the message, or any action or omission taken by you in reliance on it, is prohibited and may be unlawful. Please immediately contact the sender if you have received this message in error. Thank you. ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ **************************************************************************** **************************************** This message may contain confidential information. If you are not the intended recipient please inform the sender that you have received the message in error before deleting it. Please do not disclose, copy or distribute information in this e-mail or take any action in reliance on its contents: to do so is strictly prohibited and may be unlawful. Thank you for your co-operation. NHSmail is the secure email and directory service available for all NHS staff in England and Scotland NHSmail is approved for exchanging patient data and other sensitive information with NHSmail and GSI recipients NHSmail provides an email address for your career in the NHS and can be accessed anywhere For more information and to find out how you can switch, visit www.connectingforhealth.nhs.uk/nhsmail **************************************************************************** **************************************** ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/