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Hello, I have a set of old data that were preprocessed (realignment, smoothing, normalization) using SPM99. We recently wanted to verify that the changes to the statistical machinery of SPM in subsequent versions do not impact results. So, I used SPM8b to redo the first level analysis of a group of subjects using the realigned, smoothed, normalized images from SPM99. The results were perfect, with statistical values and local maxima coming out nearly identical for every subject, however the coordinates of these maxima are flipped. For example, one subject's global maximum is at 56 -68 -4 in 99 and SPM8b is now reported it as -56 -68 -4. Moreover, these coordinates are flipped even though check reg (and any other image viewing software I try) show the relevant con files as being in the exact same orientation. So, it is only the Results function that is reading these data differently. Obviously the SPM99 con is in analyze format whereas the SPM8 con is in NIFTI, so is there anything in the header that would cause the Results, but not the Check Reg function to view these images different? Thank You, Brandon Abbs -------------------------------- Brandon Abbs, Ph.D. Postdoctoral Research Fellow Harvard Medical School Brigham and Women's Hospital 1620 Tremont Street, BC-3-34 DWH Boston, MA 02120 Phone: 617-525-8641 Fax: 617-525-7900 E-Mail: [log in to unmask] -------------------------------- The information in this e-mail is intended only for the person to whom it is addressed. If you believe this e-mail was sent to you in error and the e-mail contains patient information, please contact the Partners Compliance HelpLine at http://www.partners.org/complianceline . If the e-mail was sent to you in error but does not contain patient information, please contact the sender and properly dispose of the e-mail.