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Dear all, Sorry to have to send out an email, I tried to post to the SPM list online, but JISCmail kept telling me I wasn't authorized to post to the SPM list (despite re-registering twice). I have one participant, whose brain I cannot seem to be able to coregister. I have four runs of an experimental paradigm. I have reoriented the anatomical image, and reoriented all of the functional images based on a reorientation I performed for the final scan of the second run to the EPI template. I then realigned the functional images to the final scan in the second run, and resliced the mean image only. I tried to coregister the mean functional image to the anatomical, but the anatomical image is always higher than the mean functional image. I have tried to reorient the functional images and re-run the realignment on the altered functional images, but no matter how much I move my functional images upwards, the coregistration process always gives me the same output (the anatomical image being much higher than the mean functional image). This only seems to happen with one participant, I haven't encountered a coregistration error with any other participant. Is there anyone who might be able to shed some light on this issue for me please? I know the basics of SPM5 and MATLAB, but I am by no means an expert, so I would really appreciate a response suitable 'for dummies' if possible. Many thanks, Daphne Garcia ******************************** Daphne Garcia PhD Candidate MRC Institute of Hearing Research University Park, Nottingham NG7 2RD Tel: 0115 951 8508 ext. 243 Fax: 0115 951 8503 ******************************** This message has been checked for viruses but the contents of an attachment may still contain software viruses, which could damage your computer system: you are advised to perform your own checks. Email communications with the University of Nottingham may be monitored as permitted by UK legislation.