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Hi All! Does it make sense to orthogonalise an interaction wrt the components (main EVs) of that interaction? Is the regressor more or less plausible and explainable then? To my mind orthogonalising is inevitable when the interaction regressor is strongly correlated with the main EVs, else the results become too ambiguous. On the other hand the more EVs I orthogonalise with, the less probable it becomes to find activations with that regressor. Is that right, or is there something really bad about orthogonalising especially in combination with interactions I don’t take into consideration? Thanks in advance Georg