The Institute of Cancer
Research is offering a fully funded PhD studentship in the Chromatin Regulation
Team in the Section of Structural Biology, including tuition fees and, stipend.
The Chromatin Regulation team is focused on understanding the molecular
mechanisms that determine the targeting and regulation of the enzyme complexes
involved in the epigenetic signalling process. This project will determine how
the mixed lineage leukaemia protein (MLL), the principle methyltransferase in
gene activation, is linked to the cell cycle by its interaction with partner
proteins such as the Host Cell Factor.
The studentship will give the
opportunity to be trained in structural biology techniques, principally X-ray
crystallography, and a range of biophysics and biochemistry approaches and
apply this to a project in the rapidly developing field of epigenetic control
of gene regulation. The Section of
Structural Biology at ICR researches the molecular basis of biological
processes to improve our understanding of the underlying mechanisms of cancer
and applies this research to the development of better cancer therapeutic agents.
The Institute of Cancer
Research (a College of the University of London) is a world-class cancer
research organisation with HEFCE RAE ratings of international excellence across
all of its research programmes. In partnership with The Royal Marsden NHS
Foundation Trust we form the largest comprehensive cancer centre in Europe,
dedicated to research that extends from epidemiology, genetics and molecular
biology, through drug discovery and development, to cancer diagnosis and
patient treatment. This makes us uniquely placed to work towards our vision
that people may live their lives free from the fear of cancer as a life
threatening disease.
Applications are invited
from suitably-qualified graduates or final year undergraduates who hold or
expect to gain a first/upper second class honours degree or equivalent in
Biology or a related subject. The successful candidate will undertake a four
year research training programme, starting in September 2009, under the
guidance of Dr Jon Wilson. The successful applicant will receive an annual
stipend - £19,096 (inner London - Chester Beatty Laboratories, Fulham Road).
For further details on this
studentship please visit: www.icr.ac.uk/phds. To apply please email [log in to unmask]
for an application form. The closing date for applications is 19th June
2009."
The Institute of Cancer Research: Royal Cancer Hospital, a charitable Company Limited by Guarantee, Registered in England under Company No. 534147 with its Registered Office at 123 Old Brompton Road, London SW7 3RP.
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