I tend to agree with Tim, especially as the UK has a dubious record with most cancers. I am probably teaching my grandmother how to suck eggs, but here is a reference regarding CA-125 in ovarian cancer http://www.ovariancancer.jhmi.edu/ca125qa.cfm Regards David Brown --- On Mon, 29/6/09, Bradbury Wayne (RNL) North Cumbria University Hospitals <[log in to unmask]> wrote: From: Bradbury Wayne (RNL) North Cumbria University Hospitals <[log in to unmask]> Subject: CA-125 To: [log in to unmask] Date: Monday, 29 June, 2009, 11:13 AM Hello all, Is anybody else seeing a surge in requests from primary care for CA-125 on women with “Abdominal bloating ?ovarian malignancy?” I think this is related to an article in the BMJ on 4th June where a patient suggests her late diagnosis of ovarian cancer could have been prevented if only her GP had asked for a CA-125. http://www.bmj.com/cgi/content/full/338/jun04_2/b2072 I am declining these requests. Am I wrong? Wayne Bradbury. Mr WH Bradbury Consultant Biochemist Biochemistry Department Cumberland Infirmary CARLISLE Cumbria CA2 7HY Tel: 01228 814521 Fax: 01228 814831 E-mail: [log in to unmask] ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/ ------ACB discussion List Information-------- This is an open discussion list for the academic and clinical community working in clinical biochemistry. Please note, archived messages are public and can be viewed via the internet. Views expressed are those of the individual and they are responsible for all message content. ACB Web Site http://www.acb.org.uk List Archives http://www.jiscmail.ac.uk/lists/ACB-CLIN-CHEM-GEN.html List Instructions (How to leave etc.) http://www.jiscmail.ac.uk/