Hallo SPM users,

I have a problem with negative beta weights. In our emotion regulation study we found anterior cingulate cortex (ACC) activation modulated by regulation direction. The point is, that the full-factorial model revealed negative beta weights for the ACC in all conditions. As far as I know, a negative beta weight can not be interpreted as reduced activation. So I am not sure how to interpret the negative betas. Thanks for help on this topic.
Regards,
Elisa Steinfurth