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Hi Rui Very easy to use is EsyPred3D : http://www.fundp.ac.be/sciences/biologie/urbm/bioinfo/esypred/ Also good performance server is 3d-JIGSAW : http://bmm.cancerresearchuk.org/~3djigsaw/ Hope it helps Cheers Francisco > Hi, All > Suppose I have two proteins A and B, they are structurally homologous, > however the sequence identity is only about 20%. A has crystal structure > available, so if I want to model protein B, what's the best way to do it? > I > don't think I can just thread the sequence of B to A structure because the > number of residues are different and there might be gaps and insertions in > the alignment. Any suggestions of good programs? > > Thanks. > > Rui > -- ----------------------------------------- Francisco J. Enguita, Ph.D. Host-pathogen Interactions Group Macromolecular Crystallography Laboratory ITQB EAN, Av. da República 2781-901 Oeiras Portugal Phone : +351-21-4469663 Fax : +351-21-4433644 E-mail : [log in to unmask] -----------------------------------------