Post-doctoral positions are available in the Netherlands Cancer Institute in the groups of Tassos Perrakis and Titia Sixma respectively (http://xtal.nki.nl).

 

The Netherlands Cancer Institute (http://www.nki.nl) is a center of excellence with a high standard of biological research and an interactive international atmosphere. It is located in Amsterdam, with all its cultural amenities, close to Schiphol airport.

 

The groups are closely associated and have an interest in structural studies coupled to functional analysis, combined with activities in method development for structural biology. Our department also hosts the newly established "Protein Facility" with equipment that includes high throughput crystallization and crystal visualization robotics both for nano-drop and Fluidigm micro-fluidics experiments, an X-ray facility (with Micro-star Ultra source from Bruker and a MarDTB), Biacore surface plasmon resonance, isothermal titration calorimetry (ITC), static light scattering (MALLS) and others. The Protein Facility has funds to establish both an automated protein expression platform  and a mass-spectrometry unit.

 

The project in the laboratory of Titia Sixma is focused at the interface of  ubiquitin (de)conjugation and DNA repair. The projects in Tassos Perrakis group is in the field of DNA replication licensing and/or proteins that regulate mitotic progression.

 

We are looking for enthusiastic researchers with experience in protein crystallo graphy, molecular biology and/or biochemistry. Applicants should write an e-mail with CV and names of three references to [log in to unmask] or [log in to unmask]