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***SECOND ANNOUNCEMENT***

Workshop on Parameter Estimation for Dynamical Systems

Date: 8-10 June, 2009

Location: EURANDOM, Eindhoven, The Netherlands

Summary: Systems of ordinary differential equations (ODEs) play an important role in modelling various phenomena that arise in fields as diverse as physics, biology, engineering, chemistry, pharmacology and others. In many cases these systems are nonlinear, which means that in general no analytic solution exists and one has to rely on numerical solutions. Such systems usually depend on constants, or parameters in statistical terminology. For instance, in biomolecular applications these parameters describe interaction rates and initial concentrations of various molecules relevant to a given biomolecular process. In order to obtain a model useful in practice, it is critical to know these parameters. Since in most cases they are not known beforehand and cannot be measured directly in the lab, they have to be inferred based on measurements of various variables related to the process at hand. However, measurements in general are subject to some measurement error. It also might be the case that not all relevant variables are observed due to technical complications, high cost of experiments, and other reasons. Typically, problems are complicated further by the fact that the dimensions of both the ODE system as well as the parameter space are high. Hence estimation of parameters of ODE systems is a challenging problem that lies at an intersection of several theoretical and applied fields. The aim of the workshop is to provide a meeting place for researchers in the area. They will review different methods used to tackle the problem, assess the achieved progress and identify future research directions.

Invited speakers: Nicolas Brunel (Évry), David Campbell (Vancouver), Pieter Hemker (Amsterdam), David Lunn (London), Kimberley McAuley (Kingston), James Ramsay (Montreal), Eberhard Voit (Atlanta), Victor Zavala (Argonne).

Programme: The preliminary programme is available on the workshop website.

Registration: To register, please visit the workshop website. There is no closing date, but the number of places is limited. There is no registration fee. Participants will be given the opportunity of giving talks on their own research.

Organisers: Chris Klaassen (Universiteit van Amsterdam), Shota Gugushvili (EURANDOM) and Bart Bakker (Philips Research).

For more information please visit the workshop website at

http://www.eurandom.tue.nl/workshops/2009/PEDS/PEDS_main.htm