Dear
collective neurone
Interesting
set of results on a 20yr old male presenting with “fluid retention”,
lack of libido and ED to a GP
Initial
endocrine request was for testosterone
We
added the gonadotrophins and were slightly puzzled by the LH
Added
SHBG, Oestradiol, HCG (just in case it was massive, although the ROCHE assay
should not suffer from cross reactivity now) and AFP
All
assays are from ROCHE platform
ALBUMIN
51H
35-50
CALCIUM
2.16
2.05-2.55
TSH
2.07
0.35-4.5
HCG
<1
0-4
FSH
3.2
1.5-12.4
LH
17.7H
1.7-8.6
PRLOLACTIN
282 86-324
OESTRADIOL
200H 28-156
SHBG1
28
10-80
TESTOSTERONE
41.0H 9.9-27.8
AFP
1
0-6
Assumed
oestradiol was coming from the aromatisation, still didn’t explain LH
? LH
(oma)
Before
rushing to assay finder to see the post carter going price for alpha sub units.
We asked the GP to see the chap had been trawling the net for medications, and
he had J
Turns
out hes been taking something called “extreme activate”
Its
new and designer and it very clever stuff. Not only has a compound that
competes for SHBG therefore raising free testo. It also has something called
Ceylon Spinich (Basella Alba) that stimulates Lydig cells and together
with something called Icarin (better known to the initiated as “Horny
Goat Weed) seems to convince the anterior pituitary that there is no
testosterone around.
Activate
extreme seems to be given the thumbs up by all the body building websites so
expect plenty of whacky male sex hormone results to hit the duty biochemists
computer screens real soon now.
Have
a good weekend
John
“pathology post carter?, pretty much the same in the
sunny southwest”