Dear Fiona,
There are one or two problems with Lucozade. The larger volume needed (411 mL) is probably not going to matter, given that patients can drink water before the OGTT. More importantly, however, is the question of whether the presence of sodium in the liquid can somehow influence the rate of uptake of glucose by Na+/glucose co-transporters. There is some indirect evidence to suggest that sodium (and aldosterone) can or may. Add to this the uncertainties or the mistakes made in buying the formulations that contain fructose and caffeine.
You can use either Polycal or Maxijul (both come in powder as well as flavoured liquid), but the easiest is to use Dr. Reddy's lemon-flavoured glucose that comes specifically in 75-gram sashets for this purpose at someting like 80p each (cheaper than Lucozade as well!).
Bets wishes,
Reza
Reza Morovat
Clinical Biochemist
Oxford
> Date: Fri, 15 May 2009 15:16:08 +0100
> From: [log in to unmask]
> Subject: OGTTs and Lucozade
> To: [log in to unmask]
>
> I know this subject has appeared in the past, but I was wondering if anyone
> could point me in the direction of the latest information on the use of
> Lucozade in OGTTs - different formulations and volumes etc that can be used.
> I have tried various other avenues and hit several brick walls so far!
>
> We are auditing how our GPs perform OGTTs, so I would also be interested to
> hear from anyone who has done anything similar, or whether labs produce
> guidance for their GPs and/or patients on the procedure. We were interested
> to note that the WHO criteria document
> (http://www.who.int/diabetes/currentpublications/en/) does not specifically
> state the levels of activity permissible during the test, or whether the patient
> can eat or drink during the 2 hours!
>
> Many thanks, Fiona
>
>
> Dr Fiona Riddoch
> Senior Clinical Biochemist
> Department of Clinical Biochemistry & Immunology
> Kingston Hospital
> x 3299 (direct dial 020 8934 3299)
>
> ACB South London Trainee Representative
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