Dear all, We have an event-related fMRI study consisting of an experimental (A) and a resting (B) session. Within each session participants view emotion (i.e. A1 or B1) and neutral (i.e. A2 or B2) stimuli. The design is as follows: Session A Session B Emotion 1 2 Neutral 1 2 We want to compare the brain activation of emotion perception in A with that in B. We propose a t-contrast, controlling for the effect of head movements: (A1 - A2) - (B1 - B2) = A1 - A2 - B1 + B2 Are we correct? Or would you think there is/are other more appropriate way(s)? Look forward to receiving your comments. Regards, wk