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I have noticed that a significant majority of crystallizations are done in hanging- rather than sitting-drop configuration, and considering the significant extra labor involved in hanging drops, can only understand this preference as a historical bias. I understand that sometimes one technique works and not the other, but all things being equal, why is hanging drop still "hanging around?" Any insights appreciated... Jacob Keller ******************************************* Jacob Pearson Keller Northwestern University Medical Scientist Training Program Dallos Laboratory F. Searle 1-240 2240 Campus Drive Evanston IL 60208 lab: 847.491.2438 cel: 773.608.9185 email: [log in to unmask] *******************************************