Hi Erin, I find this really puzzling. Would you be able to send us your data? This, and the *exact* commands you've been running, will hopefully help us find the problem and sort it out. You can upload the data at the website: http://www.fmrib.ox.ac.uk/cgi-bin/upload.cgi Once you've done that, send us the reference number and the commands you've been running. All the best, Mark Mazerolle, Erin wrote: > Hi again Steve et al > > I have a little bit more evidence related to the problem that I thought I would share, given that you mentioned you are surprised that the dofs are changing the end-slice behaviour. > -sometimes increasing the paddingsize helps, but sometimes it doesn't > -even when I use dof = 7, the end slices look fine (the problem only occurs for dof = 6) > -it is always the most inferior slice > -the problem is worsened at higher b-values (larger parts of the most inferior slice are cut off, again only with dof = 6) > > Given the last point, I am wondering if this is more of a problem with using flirt on volumes with very low signal, rather than a problem with movement in my data? I'm very interested to hear any thoughts people might have. Would it be better to just run flirt on my b = 0 images, and interpolate the motion corrections on the intervening diffusion weighted images? > > Thanks again! > > Erin > > > ================================================================================================ > > > Hi - I'm a little surprised that you would get different end-slice > behaviour in the dof=6 and 12 cases, but if this is just due to very > slight rotations out of volume then you can reduce that with the - > paddingsize option. I would not use mcflirt as it is not at all > optimised for this scenario. > > Cheers. > > > On 9 Mar 2009, at 20:53, Mazerolle, Erin wrote: > > >> Hi Steve et al >> >> Thanks very much. I tried this but I find that it results in parts >> of my >> most inferior slices being cut off. I checked using mcflirt and it >> doesn't appear that I have motion that is larger than my slice >> thickness >> (3mm slices versus 0.002 radians & 0.6mm motion params). Do you >> think it >> would be reasonable to use mcflirt instead of the flirt call in >> eddy_correct? I am worried that mcflirt might get confused by the >> differences in intensity between diffusion weighted versus b=0, but I >> don't understand how eddy_correct 's flirt call handles these >> intensity >> differences either. >> >> I should also note that when I use 12 DOF (i.e., eddy_correct 's >> default >> flirt call), my inferior slices are not cut off. Basically the only >> problem with using the 12 DOF is conceptual - there shouldn't be any >> shearing & stretching caused by eddy currents in my spiral data (I >> believe eddy currents are more likely to appear as blurring in spiral >> acquisitions). >> >> Thanks for any ideas! >> >> Erin >> >> >> >> >>> Hi - you're mostly right, you won't get eddy correction in this case >>> but you can still correct for head motion. However, you may as well >>> constrain the degrees-of-freedom to be rigid body in this case, so >>> take a local copy of eddy_correct and add the following flag to the >>> flirt call (just before the ">>"): >>> >>> -dof 6 >>> >>> Cheers. >>> >> >> On 16 Feb 2009, at 18:37, Mazerolle, Erin wrote: >> >> >>> Hello, >>> I was hoping someone could tell me if it is valid to run FSL's eddy >>> current correction with diffusion data collected using a spiral >>> trajectory. I don't imagine it would be able to correct for eddy >>> currents due to the difference in trajectory, but can it still do >>> the motion correction across images with different bvalues? >>> Thanks! >>> Erin >>> > >