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Greetings All -- I am posting this on behalf of the HR department here at Exelixis. Our Fermentation department provides all of our protein resources for high-throughput assay, cell biology and structural biology. Our structural biology protein "consumption rates" are comparable to the larger structural genomics initiatives, so someone with that sort of background and experience would be an especially ideal candidate. Please mention this to anyone you think is appropriate and might be interested in relocation to the San Francisco Bay Area of sunny* California! Cheers, Tom *Full disclosure: yes, we have some fog too... But snow is generally properly kept to where it belongs: about a 3 hour drive into the Sierra Nevada mountains... :) Here are the details: Assistant Research Scientist II Job ID #: 667 Location: South San Francisco, CA Position Type: Full-Time Regular Department: Genome Biochemistry Education Required: Bachelors Degree Experience Required: 1 - 3 Years Apply: Online at www.exelixis.com We are seeking a professional to join our fermentation team in a hands-on laboratory role. Duties include cell culture maintenance, scale-up and optimization of protein expression, and biomass production for multiple drug discovery projects. The successful candidate will assist in planning and development of new methodologies and laboratory protocols to improve the efficiency and productivity of the fermentation process. You will prepare and organize data for presentation and project status reports at individual, group, and departmental research meetings. You will be expected to maintain familiarity with current scientific literature relevant to the research experiments and programs. BS/BA degree in Biology, Biochemistry, or Chemical Engineering and one year of related experience; or MS/MA degree in related discipline or combination of experience and education/training. Familiarity with protein expression analysis tools such as Western blotting, SDS-PAGE, and activity analysis are desired, as would knowledge of expression construct design and protein purification techniques. The qualified candidate should have experience in the production of recombinant proteins from systems such as E. coli and/or insect cells using fermentors and bioreactors from 5 to 80 L scale. Must be able to lift at least 40 lbs. This email (including any attachments) may contain material that is confidential and privileged and is for the sole use of the intended recipient. Any review, reliance or distribution by others or forwarding without express permission is strictly prohibited. If you are not the intended recipient, please contact the sender and delete all copies. Exelixis, Inc. reserves the right, to the extent and under circumstances permitted by applicable law, to retain, monitor and intercept e-mail messages to and from its systems.