Dear group

 

I wish to use this list serve to bring to every ones attention a paper just published by Dr.George Schwartz. Dr. Schwartz published in the Journal of American Society of Nephrology an excellent paper describing an update to “Schwartz Equation” used to estimate pediatric GFR.

 

Of note:

The equation uses creatinine as measured with an enzymatic method.

The enzymatic method used is traceable to the new IDMS reference method procedure.

The updated equation was not validated for use with Jaffe based creatinine.

 

As these equations are used for pharmacy dosing, it is so important that laboratories and pharmacies communicate with one another regarding how the creatinine assay is referenced (ie non IDMS or IDMS traceable) as well as the GFR equation is use (is the equation based on IDMS creatinine).

 

The paper reference is

New Equations to Estimate GFR in Children with CKD

George J. Schwartz, Alvaro Munoz, Michael F. Schneider, Robert H. Mak,Frederick Kaskel, Bradley A. Warady,  and Susan L. Furth

J Am Soc Nephrol: –, 2009

 

A second supporting paper is

 

Estimating Equations for Glomerular Filtration Rate in Children: Laboratory Considerations

W. Greg Miller Clinical Chemistry 55:3 402–403 (2009)

 

I hope this is an appropriate use of this listserve.

 

Sincerely

 

Joe I