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Not sure if it's been mentioned, but I personally use EnzymeX(http://mekentosj.com/enzymex/ ) . Also, I find their PDF library organizer Papers (http://mekentosj.com/papers/ ) to be exceptional. Cheers FR On Jan 28, 2009, at 1:47 AM, Darren Hart wrote: > Hello, > After several years of offering the molecular biology software > VectorNTI > free to the academic community (their "open access program") and > building > up a huge user base, Invitrogen have suddenly announced that they > will no > longer renew these free licences and the existing ones will be left to > expire within the year. There are heavy renewal fees for anyone > wishing to > continue use of this software. > > Can anyone recommend decent alternative PC compatible alternatives? > Main > uses are construct and primer design, plus simple quick alignments, > sequence data analysis etc. The database structure for storing > sequences > was pretty useful also. > > Ideally free, otherwise reasonably priced. I've seen CLCbio and > Geneious > have products, both free and paid. Any experience? > > Thanks, > Darren > EMBL Grenoble > > ps anyone using VNTI might consider a backup of their work by > exporting > files to .gb format. I don't know if a locked up (expired) version > permits > this and you will have no notice that it is about to expire. > > --------------------------------------------- Francis Reyes M.Sc. 215 UCB University of Colorado at Boulder gpg --keyserver pgp.mit.edu --recv-keys 67BA8D5D 8AE2 F2F4 90F7 9640 28BC 686F 78FD 6669 67BA 8D5D