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You can use the CCP4 program sftools. You will need to use the program twice if you want to keep the differences positive ie F1 - F2 if F1>F2 and F2 - F1 if F2>F1 Adam On Thu, 29 Jan 2009, Rana Refaey wrote: > > Hi, > > I was wondering if anyone knows what programme I need to use to subtract the Fobs of two different crystals from each other. > > Regards, > Rana > > _________________________________________________________________ > Invite your mail contacts to join your friends list with Windows Live Spaces. It's easy! > http://spaces.live.com/spacesapi.aspx?wx_action=create&wx_url=/friends.aspx&mkt=en-us