Hello
In the November 2008 issue of the Annals there is a letter by a Dutch group (Ross et al.) which describes the use of affinity chromatography columns to detect heterophilic antibodies (based on an earlier paper by Koper et al. in Clin Chem Lab Med.). Though more labour intensive, this is claimed to be superior to the blocking tubes in common use (e.g. Skybio).
How widely is this technique used in practice? For future reference does any lab incorporate this technique routinely in the assessment of potential HAMA/HA interference rather than relying on other simpler interference checks?
Regards
Steve
________________________________________________________
Dr Stephen Frost
Department of Clinical Biochemistry and Immunology
Brighton and Sussex University Hospitals NHS Trust
The Princess Royal Hospital
Lewes Road
Haywards Heath
West Sussex
RH16 4EX
Tel 01444 441881 ext 8197
Fax 01444 414051
email [log in to unmask]
Views expressed are my own and not necessarily those of the Trust.
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