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Hi Saad!
That is fantastic news!
I am curious if it changes my waytotals!
Thanks for your high presence here in the list!
Markus


2008/12/3 Saad Jbabdi <[log in to unmask]>

>
>
> Hello Saad!
>
> ...so I would be surprised if there were 50 articles published that are
>> using it!
>
> Sorry. I was just guessing out of my guts...  I overestimated the
> importance of probtrackx ;-)
>
>
> I was actually referring to waytotal. I'm sure there are many papers using
> probtrack(x) :-)
>
>
>
> Can the patch also be installed to FSL 4.0.4?
>
>
> You can use the probtrackx binary (copy it into $FSLDIR/bin), but you can't
> mix the source files if you need your own build...
>
>
> Cheers,
> Saad.
>
>
>
>
> Thank you for your support!
> Markus
>
>
> 2008/12/1 Cherif Sahyoun <[log in to unmask]>
>
>> I see, so this will be too dependent on how much overlap there is at the
>> core...
>> Any other possibilities? maybe using a percentile? (upper output of
>> fslstats -r)?
>>
>>
>> ------------------------------------------------------------------------------------------
>> Cherif P. Sahyoun                                               HST-MEMP
>>
>> Developmental Neuroimaging of Cognitive Functions
>>
>> C: 617 688 8048
>> H: 617 424 6956
>> [log in to unmask]
>>
>> "Live as if this were your last day. Learn as if you'll live forever"
>> Gandhi
>>
>> -------------------------------------------------------------------------------------------
>>
>>
>>
>> On Mon, Dec 1, 2008 at 5:41 PM, Matt Glasser <[log in to unmask]> wrote:
>> > I don't think using the max value of the fdt_paths is a good idea.  That
>> > will vary depending on how closely packed the samples are at the
>> narrowest
>> > point of the tract.  For example if you have a 100000 sample pathway
>> that at
>> > its narrowest point goes through a single voxel, that voxel's value
>> would be
>> > 100000, and that would be the max of the fdt_paths.  If you had a
>> separate
>> > 100000 sample pathway that at its narrowest point was divided evenly
>> among 4
>> > voxels, the maximum value of the fdt_paths would be 25000.  Normalizing
>> > based on this number would give you very different probability values
>> across
>> > the entire pathway, even if the two were otherwise identical.
>> >
>> > Peace,
>> >
>> > Matt.
>> >
>> > -----Original Message-----
>> > From: FSL - FMRIB's Software Library [mailto:[log in to unmask]] On
>> Behalf
>> > Of Cherif Sahyoun
>> > Sent: Monday, December 01, 2008 4:10 PM
>> > To: [log in to unmask]
>> > Subject: Re: [FSL] question on old and new waytotals
>> >
>> > Hi Saad,
>> >
>> > Can you talk about the implications of using something other than the
>> > waytotal for normalizing? I'll get you started :)
>> >
>> > - using waytotal would give the conditional probability of going
>> > through a given voxel, given that there is a path.
>> > - using the ROI_size*samples would give the absolute probability of
>> > going through a voxel (on the path)
>> > What to you think of using the max value of the fdt_paths? That should
>> > give a normalized conditional probability similar to using waytotal
>> > (though obviously we important differences since now we are forcing
>> > the most likely voxels to have a probability of 1, which was not the
>> > case using waytotal)...
>> > If what one wants is just to normalize across subjects to be able to
>> > compare mean p of a tract, I guess that would work?
>> >
>> > Best,
>> > Cherif
>> >
>> >
>> ----------------------------------------------------------------------------
>> > --------------
>> > Cherif P. Sahyoun                                               HST-MEMP
>> >
>> > Developmental Neuroimaging of Cognitive Functions
>> >
>> > C: 617 688 8048
>> > H: 617 424 6956
>> > [log in to unmask]
>> >
>> > "Live as if this were your last day. Learn as if you'll live forever"
>> > Gandhi
>> >
>> ----------------------------------------------------------------------------
>> > ---------------
>> >
>> >
>> >
>> > On Mon, Dec 1, 2008 at 4:54 PM, Saad Jbabdi <[log in to unmask]>
>> wrote:
>> >> Hi Markus,
>> >> When you say 50 papers, you must be thinking of the seed_to_target
>> values,
>> >> not waytotal, am I right? The output of seed_to_target is NOT
>> >> underestimated, it is only waytotal.
>> >> the waytotal file is a recent output in probtrackx, so I would be
>> > surprised
>> >> if there were 50 articles published that are using it!
>> >> To answer your question, I think it is quite hard to predict the
>> behaviour
>> >> of waytotal as it is now, so I would recommend re-running your analysis
>> > with
>> >> the patch to come if you are planning to use waytotal.
>> >> Cheers,
>> >> Saad.
>> >>
>> >> On 1 Dec 2008, at 17:20, Markus Gschwind wrote:
>> >>
>> >> That is very good news! Thank you so much!
>> >>
>> >> However, I am really curious if there is an officially recommended way
>> of
>> >> dealing with this underestimation. Roughly guessed, there are about 50
>> >> publications using those "old" waytotals and if I contribute another
>> one,
>> >> now that it is known that those values are not always true...
>> >> Should all the people who are still working with FSL 4.0.x really
>> restart
>> >> the whole analyis in FSL 4.1?
>> >>
>> >> Would there be another way?
>> >>
>> >> Many regards,
>> >> Markus
>> >>
>> >>
>> >>
>> >>
>> >>
>> >> 2008/12/1 Saad Jbabdi <[log in to unmask]>
>> >>>
>> >>> Hi All,
>> >>>
>> >>> The patch -should be- available tomorrow :-)
>> >>>
>> >>> Thank you all for pointing this out!
>> >>>
>> >>> Cheers,
>> >>> Saad.
>> >>>
>> >>>
>> >>> On 28 Nov 2008, at 20:23, Martin Kavec wrote:
>> >>>
>> >>>> Thanks a lot Saad,
>> >>>>
>> >>>> at least we helped to point out the problem. Could you please let us
>> >>>> know,
>> >>>> when we could expect the patch?
>> >>>>
>> >>>> Thanks,
>> >>>>
>> >>>> Martin
>> >>>>
>> >>>> On Friday 28 November 2008 19:50:43 Saad Jbabdi wrote:
>> >>>>>
>> >>>>> Hi Markus (and Yan Liu),
>> >>>>>
>> >>>>> I am terribly sorry, but just realised that I haven't included that
>> >>>>> fix to the released FSL!!! You will need to wait for the next patch
>> >>>>> now...
>> >>>>>
>> >>>>> And to answer your question, in principle it should underestimate
>> >>>>> waytotal by 50% on average if you set the option "--randfib".
>> >>>>> Otherwise it is difficult to predict by how much it will
>> underestimate
>> >>>>> it for each data set..
>> >>>>>
>> >>>>> Again, I am sorry for any inconvenience.
>> >>>>>
>> >>>>> Cheers,
>> >>>>> Saad.
>> >>>>
>> >>>>
>> >>>> --
>> >>>> **********************************
>> >>>> Senior Clinical Research Associate
>> >>>> MRI Unit of the Department of Radiology
>> >>>> Erasme Hospital
>> >>>> Lennik Street 808
>> >>>> B-1070 Brussels
>> >>>> BELGIUM
>> >>>>
>> >>>> tel: +32-2-555-4325
>> >>>> fax: +32-2-555-3994
>> >>>> email: [log in to unmask]
>> >>>> **********************************
>> >>>>
>> >>>> -----------------------------------------------
>> >>>> Find a way, or make one!
>> >>>>
>> >>>
>> >>> Saad Jbabdi
>> >>> Oxford University FMRIB Centre
>> >>>
>> >>> JR Hospital, Headington, OX3 9DU, UK
>> >>> +44 (0) 1865 222545  (fax 717)
>> >>> www.fmrib.ox.ac.uk/~saad <http://www.fmrib.ox.ac.uk/%7Esaad>
>> >>
>> >>
>> >>
>> >> --
>> >> Dr. med. Markus Gschwind, M.D.
>> >> Laboratory for Neurology and Imaging of Cognition
>> >> Dept of Neurosciences
>> >> University Medical Center (CMU)
>> >> 1 Michel-Servet - 1211 GENEVA - CH
>> >>
>> >> Tel 0041 (0) 22 379 5324
>> >> Fax 0041 (0) 22 379 5402
>> >> email: [log in to unmask]
>> >> http://labnic.unige.ch
>> >>
>> >> Saad Jbabdi
>> >> Oxford University FMRIB Centre
>> >> JR Hospital, Headington, OX3 9DU, UK
>> >> +44 (0) 1865 222545  (fax 717)
>> >> www.fmrib.ox.ac.uk/~saad <http://www.fmrib.ox.ac.uk/%7Esaad>
>> >>
>> >>
>> >>
>> >>
>> >>
>> >>
>> >
>>
>
>
>
> --
> Dr. med. Markus Gschwind, M.D.
> Laboratory for Neurology and Imaging of Cognition
> Dept of Neurosciences
> University Medical Center (CMU)
> 1 Michel-Servet - 1211 GENEVA - CH
>
> Tel 0041 (0) 22 379 5324
> Fax 0041 (0) 22 379 5402
> email: [log in to unmask]
> http://labnic.unige.ch
>
>
> Saad Jbabdi
> Oxford University FMRIB Centre
>
> JR Hospital, Headington, OX3 9DU, UK
> +44 (0) 1865 222545  (fax 717)
> www.fmrib.ox.ac.uk/~saad <http://www.fmrib.ox.ac.uk/%7Esaad>
>
>
>
>
>
>
>


-- 
Dr. med. Markus Gschwind, M.D.
Laboratory for Neurology and Imaging of Cognition
Dept of Neurosciences
University Medical Center (CMU)
1 Michel-Servet - 1211 GENEVA - CH

Tel 0041 (0) 22 379 5324
Fax 0041 (0) 22 379 5402
email: [log in to unmask]
http://labnic.unige.ch