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I would say that all crystals represent hyper-oligomeric structures,  
but never mind, I know what you mean ;-)

the E. coli EF-Tu:EF-Ts complex is a good example - the structure  
clearly indicates an (EF-Tu:EF-Ts)2 dimer, and the T. thermophilus EF- 
Tu:EF-Ts is even a disulphide-linked dimer.
However, all solution studies indicate that the E.coli EF-Tu:EF-Ts  
complex is in fact a monomeric complex.

Poul
On 11/12/2008, at 17.09, Santarsiero, Bernard D. wrote:

> In parallel with the discussion around this off-CCP4-topic, are they  
> any
> good examples of the opposite case, where the protein is a monomer in
> solution (as evident from light scattering, MW determination through
> centrifugation, EPR, etc.) but crystallizes as a dimer or higher  
> multimer?
>
> Bernie Santarsiero
>