Dear John, My MATLAB coding knowledge is limited, but I looked at the functions you mentioned and I sort of understand. I am able to produce the composition (A o B) as a y_warp.nii. Is there a way to translate j and/or y (from dartel3 function) into an *sn.mat file, or modulate an image by j or y? How do y and j relate to the matrices Affine and Tr? Tr for our images have the dimensions 6 x 9 x 10 x 3 -- is that always the case, and can you tell me what each of these dimensions refers to? When you used dartel3 below, how did you pick 6 as the number of recursions? Thanks again, Dana -----Original Message----- From: John Ashburner [mailto:[log in to unmask]] Sent: Wednesday, October 29, 2008 9:35 AM To: Dana Perantie; [log in to unmask] Subject: Re: [SPM] combining non-linear warps Dear Dana, There's nothing in the Deformations Utility for doing this in a nice easy way, but it could be done by working with the Jacobian fields that can be written out to disk. The toolbox/DARTEL/spm_dartel_norm.m function is used for writing normalised data. I'm not sure how your MATLAB coding is, but you could do it using some code along the lines of... N1 = nifti('u_image1.nii'); N2 = nifti('u_image1.nii'); u1 = squeeze(single(N1.dat(:,:,:,:,:))); u2 = squeeze(single(N2.dat(:,:,:,:,:))); [y1,j1] = dartel3('Exp', u1, [6 1 1]); [y2,j2] = dartel3('Exp', u2, [6 -1 1]); y3 = dartel3('comp', y1, y2); j3 = dartel3('samp',j1,y2).*j2; There'll be a bit more to it than this though. All the best, -John On Tuesday 28 October 2008 19:34, Dana Perantie wrote: > Thanks John, > The Deformations utility is going to be very helpful, and so are the > instructions in the DARTEL manual. > > Is there also a simple way to "modulate" by a flow field *without* applying > the flow field at the same time? I want to warp a whole brain image by A > and later by B, segment the output of that and then modulate the segments > by the composition (A o B). If there is not already a GUI to do that, could > you please point me to the *.m file for DARTEL's "Create Warped" so I may > pick out the modulation step from there? > > Thanks again, > Dana > > > -----Original Message----- > From: John Ashburner [mailto:[log in to unmask]] > Sent: Friday, October 17, 2008 10:16 AM > To: Dana Perantie; [log in to unmask] > Subject: Re: [SPM] combining non-linear warps > > I forgot to mention that the approach involves the Deformations utility, > available from the Tasks pulldown. There is some documentation about how > to use it in the http://www.fil.ion.ucl.ac.uk/~john/misc/dartel_guide.pdf > file (or the SPM8b manual). > > Best regards, > -John > > -----Original Message----- > From: John Ashburner [mailto:[log in to unmask]] > Sent: Friday, October 17, 2008 10:14 AM > To: Dana Perantie; [log in to unmask] > Subject: Re: [SPM] combining non-linear warps > > There's no tool for generating a new sn.mat file, but you can generate a > y_*.nii, which could be used for the same thing. > > Best regards, > -John > > On Thursday 16 October 2008 21:07, Dana Perantie wrote: > > Hello SPM list, > > Is there a way to combine non-linear warp parameters, i.e. if I warp A to > > B and B to C, is there a way to combine the *sn.mat files to make a *.mat > > representing the warp from A to C? Thank you, > > Dana