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Hi SPMers The papers of validation of co-register methods don't explain what tecnique would be better, if a rigid-body transformation or a non-rigid-body transformation. In my work i coregister MR and SPECT in SPM, but some people in departament are questioning that non-rigid transformation is more appropriate.What are your opinion about this? It's possible update the coregister routine to perform non-rigid-body transformation, or would be necessary create a specific function for this? Thanks Henrique Amaral Clinics Hospital of Ribeirão Preto of the University of São Paulo - Brazil