I was reading a very
interesting book about DNA, if you do a bone marrow stem cell transplant for
someone with leukaemia, the cells that you will have inside your bone marrow
will come from your donor. Therefore, they will also be genetically identical
to the donor. This means that a man who receives a bone marrow transplant from
a lady will have bone marrow cells that have two X chromosomes. Sometimes
people can even see a change in their blood group. Can’t remember
the author though and not really sure if this is particularly relevant.
From:
[log in to unmask] [mailto:[log in to unmask]] On Behalf Of Amanda Savage
Sent: 18 September 2008 10:55
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood
loss affecting immunity
Levels of immunity will drop post
vaccination – they will not remain at a high level. How it was explained
to me is as follows: -
Once immunity has been confirmed the body
stores this in print as a ‘memory’ that can be activated if it
comes into contact with the antigen just because the level drops it does not
mean the immune response is lowered.
Regards
Amanda Savage BSc(Hons); Sp Prac OH; RGN; DON; NEBOSH
Senior Occupational Health Adviser
Tel: 0121 380 7441
Mob: 07770863052
P Please
protect the environment - think before you print.
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-----Original
Message-----
From: [log in to unmask]
[mailto:[log in to unmask]] On Behalf
Of Sara Werry
Sent: 18 September 2008 10:50
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood
loss affecting immunity
Thanks Amanda it is always useful to have the “green
book” reiterated but my point was that although not in keeping with the
green book at the time this is what we did, and interestingly levels did drop
for no apparent reason so what has happened in the case we are debating may
have been in keeping with the general population.
Regards
Sara
From:
[log in to unmask] [mailto:[log in to unmask]] On Behalf Of Amanda Savage
Sent: 18 September 2008 10:42
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood
loss affecting immunity
Green
book says check 8 weeks after number 3 so you know they have actually responded
then boost at 5 years. If there is no response at HbAbs stage they need
checking for natural immunity or infectivity.
Regards
Amanda Savage
BSc(Hons); Sp Prac OH; RGN; DON; NEBOSH
Senior
Occupational Health Adviser
Tel:
0121 380 7441
Mob:
07770863052
P Please protect the environment - think before you print.
Unless expressly stated
otherwise, the information contained in this e-mail is confidential and is
intended only for the named recipients.
The information contained
in this e-mail may be subject to public disclosure under the Freedom of
Information Act 2000. Unless the information is legally exempt from disclosure,
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-----Original Message-----
From: [log in to unmask]
[mailto:[log in to unmask]] On Behalf
Of Sara Werry
Sent: 18 September 2008 10:40
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood
loss affecting immunity
Hi all
In a previous employment a good few years ago! Our policy was to
check serology at 3 years whatever the level after initial course and it
wasn’t uncommon for levels to of dropped from >100 to <10 we
didn’t really look for cause might have been interesting if we had at
time. Of course now with not checking levels again but just boosting at 5 years
you would never know how far levels have dropped as the theory seems to be that
if you have ever responded to the vaccine when in contact with it the levels
would raise.
All best
Sara
From:
[log in to unmask] [mailto:[log in to unmask]] On Behalf Of Milne Campbell
Sent: 18 September 2008 09:26
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood
loss affecting immunity
I have
hear of this too,
This
includes some Chemo treatments too
-----Original
Message-----
From: [log in to unmask]
[mailto:[log in to unmask]] On Behalf
Of MICHAEL COCKAYNE
Sent: 17 September 2008 20:55
To: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood loss
affecting immunity
My point is that if you haven't got any proof of a
responsive Anti-HBs from 2000 then there is no proof that her immunity has
indeed been affected.
However, I have seen someone who underwent immunotheropy and a
tranfusion and was advised by her Consultant to have all her childhood
imms courses repeated - tetnus, polio, dip ect. We also repeated her hep B
course from scratch.
Date: Wed, 17 Sep 2008 15:43:55 -0400
From: [log in to unmask]
Subject: Re: [OCC-HEALTH] Blood loss affecting immunity
To: [log in to unmask]
In
a message dated 17/09/2008 20:41:03 GMT Standard Time,
[log in to unmask] writes:
If you haven't seen any evidence of an Anti-HBs >10 from the course in 2000 then I would perform a full hep B serology, and if everything is okay offer her a second course of an alternative brand of the vaccine.
Hope this helps
Thanks for this Michael
we've sorted out her vaccination but the question was would
immunity have been affected by having had a significant blood transfusion?
Thanks
Glenn
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