Dear Jayashankar,
How refreshing it is to hear someone question how things work. Bill and
Mark are beginning to show you the way. You are ready to roll up your
sleeves and study the subject. This list of apparently solved problems
hides a wonderland of studies and hard work (some of it based on Bill's
and Mark's perspiration, and that of many others) that depend on
fundamentals in physics, biology, cryogenics, computer science, and on and
on.
Take each one and start asking questions. If your curiosity lasts, you
have a chance of making some nice advances in the field.
Bob
On Sat, 20 Sep 2008, Jayashankar wrote:
> Dear friends and crystallographers,
>
> During One of my lab meeting ,
>
> I told twinning in crystals are ok, because ccp4's recent releases just need the keyword TWIN to
> solve them,
>
> As a new generation research student, I am now confused, is that I need to learn and understand all
> programs(so many...but research does not mean relaying on them)
> to solve my crystallographic problems(is that all)....
> if you see all the queries in ccp4BB is just about undocumented or misunderstood program oriented
> questions.
>
> is that all i have to learn in crystallography in future.
> Still upto what limitations we are now in crystallography.
> this is my very naive and prime question.
>
> 1.Phase problem
> 2.twin problem
> 3.solving intrinsically disordered proteins
> 4.hetro multimeric proteins
> 5.high order oligomers
> 6.cryo crystallography
> 7.automation in high through put crystallography
> 8.radiation damage
> 9.kinetic crystallography
> 10. crystal growth research (antigravity, pressure )
> 11.stereo graphics
>
> if i am right all the above has been studied (....what we are not clear still about them),
>
> I need an answer to motivate me in doing my research in Crystallography.
>
> S.Jayashankar
> (A confused new generation research student)
> Research Student
> Institute for Biophysical Chemistry
> Hannover Medical School
> Germany.
>
>
--
=========================================================================
Robert M. Sweet E-Dress: [log in to unmask]
Group Leader, PXRR: Macromolecular ^ (that's L
Crystallography Research Resource at NSLS not 1)
http://px.nsls.bnl.gov/
Biology Dept
Brookhaven Nat'l Lab. Phones:
Upton, NY 11973 631 344 3401 (Office)
U.S.A. 631 344 2741 (Facsimile)
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