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Hi Sorry for a mixed up question about two great software. Has anybody tried to use Resolve after sharp / autosharp? i.e., escaping the Solomon step other than handedness determination and doing the density modification (& maybe NCS / building) directly with the sharp output? If so, I would appreciate any input.. I am confused with the eden file.. Cheers, Partha -- MRC National Institute for Medical Research Division of Molecular Structure The Ridgeway, NW7 1AA, UK Email: [log in to unmask] Phone: + 44 208 816 2515